You can use the NetBackup for SharePoint Server agent to back up the entire SharePoint Server farm or individual components.
For general information on backup methods in NetBackup see the NetBackup Administrator's Guide, Volume I.
More Information
About the contents of a SharePoint Server 2010 and SharePoint Foundation 2010 backup
About the contents of a SharePoint Server 2007 and Windows SharePoint Services 3.0 backup
About the contents of a SharePoint Server 2003 and Windows SharePoint Services 2.0 backup