The NDIS\Parameters subkey stores configuration data for the NDIS 5.0 interface in Windows 2000, Ndis.sys.

Ndis.sys supports communication between protocol drivers, network interface drivers, and network adapters. Ndis.sys acts as an intermediary between protocol drivers and network adapters, so that they can remain independent and allow a network adapter to support multiple network protocols, such as TCP/IP and IPX. It also allows multiple network interface drivers and multiple network adapters to co-exist within a system.