The Enterprise Vault Cache is a folder on the Enterprise Vault server that Enterprise Vault uses to store temporary files. The cache is currently used by PST Migration, FSA when the target file server is a Celerra file server, and Vault Cache.
The major use for the cache is to provide temporary storage for Vault Cache clients. If only a few Enterprise Vault clients use Vault Cache, a location with a minimum of 20GB of free space is probably sufficient. If many clients use Vault Cache, specify a location with far more free space.
As anti-virus software can potentially change data in the cache, it is important to exclude the cache location in your virus checking application.