The following scenarios must be followed if you plan to cluster Backup Exec:
Symantec highly recommends that you use the default database instance (MSDE) that Backup Exec installs if you plan to cluster Backup Exec.
Symantec also supports using a remote SQL Server instance to host the Backup Exec database. However, if you plan to use this scenario, review the following:
Only one installed instance of Backup Exec can be installed into the remote SQL Server instance on a clustered node. All other installed instances of Backup Exec in the cluster must use the default Backup Exec MSDE database instance.